How much is a flight from Panama City to Santo Domingo?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Panama City and Santo Domingo.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Panama City - Santo Domingo route.

Are there multiple airports in Panama City and Santo Domingo?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Panama City: 2 airports are active in Panama City - Pacífico International Airport, Paitilla.
• Airports in Santo Domingo: Santo Domingo - Mayo Guerrero is the only airport currently running.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Plan your journey from Panama City to Santo Domingo with ease

Use Jetcost to tailor your search — direct or connecting flights, round-trip or one-way, filtered by airline, price, travel time, or agency.

Other popular destinations

Exploring options in Venezuela? These cities are trending: Barquisimeto, Caracas, Maracaibo, Porlamar, Valencia.

Flight availability can change quickly — refresh the results if you’ve been away from the page for a while.